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InChiKey: RKAIKBRLPZSBRN-WEDXCCLWSA-N
Smiles: OC1C=CC(=CC=1)NC(=O)C1=CC=CC=C1O
with an EC50 of 20 and 100 nM
Afeletecan is an active compound
FASCIN-G2 - Fascin Inhibitor. CAS# 1569076-11-4 yamine InChiKey: RKAIKBRLPZSBRN-WEDXCCLWSA-NFASCIN G2, CAS No. 1569076 11 4, is a potent, selective and bioavailable small molecule that inhibits the actin bundling activity of fascin with Kd ~5 20 M. It specifically blocks filopodial formation, tumour cell migration and invasion in vitro. , FASCIN G2 showed very good in vivo efficacy in 4T1 mammary tumour metastasis model and in MDA MB 231 human breast tumour metastasis model. Product information CAS Number: 1569076 11 4 Molecular Weight: 385.
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